Merel's family is expanding when everybody has, is having or wants to have a baby. Annet and her husband, both in their forties, are trying to have another child with the help of doctors, when daughter Eva unexpectedly announces her pregnancy. Meanwhile, Grandpa Piet is trying to catch up with his second lay what he has missed with his now grown daughters. As a midwife, Merel knows that she cannot wait endlessly with her wish to have children, but the perfect man is nowhere to be seen. She decides to go for single motherhood. But just when the pregnancy test is positive and the hormones are coursing through her body, there is the charming paramedic Luuk who turns her whole life upside down…